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Appalachia, which stretches across 13 states, is rarely center stage during presidential campaigns. It is one of the most economically deprived regions of the country and deeply conservative.

NIH Director Francis Collins has stopped research at two leading labs for now. But an independent board of experts wants even more oversight to ensure that patient safety is the top priority.

Prince was not only a spectacular musician but also a singular performer. From the Super Bowl to the Rock and Roll Hall of Fame, he left a mark onstage.

Executives who get their firms in legal trouble could be forced to pay back bonuses retroactively.

The agreement addresses "what to do about the 2-liter diesel cars on the road and the environmental consequences resulting from their excess emissions," the Justice Department says.

The two nations topping the world in greenhouse gas emissions agreed at the Paris talks to cut way back. But critics have stalled a key part of the U.S. plan, and China's good start may be fragile.

With chiseled muscles and a natural flair for entertainment, Joanie Laurer exploded onto the scene of professional wrestling in the late 1990s. She was found dead in her apartment Wednesday.

President Andrew Jackson, who is the face of the $20, will be replaced by abolitionist leader Harriet Tubman. Lourdes Garcia-Navarro talks to Susan Ades Stone, co-founder of the group Women On $20s.

U.S. military officials are worried about the connections between ISIS and Boko Haram. U.N. Ambassador Samantha Power visited the African country of Chad, which is threatened by both groups.

Whitesburg, Kentucky, was an area once known for coal mining but most of those jobs have dried up. Limited opportunities force many residents to leave, but some are able to find their way back.