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People with tree-trunk-like legs who can't lose weight through diet and exercise may have lipedema, a lymphatic disorder. It's not clear what causes it, and most doctors aren't familiar with it.

An estimated 84 million people watched Hillary Clinton and Donald Trump in their first debate Monday, according to TV ratings data from Nielsen.

The pollution levels have a staggering impact on health, according to the report, which says: "In 2012, one out of every nine deaths was the result of air pollution-related conditions."

For the first time in a decade, someone other than Jerry Seinfeld tops Forbes' ranking of the highest-paid comedians.

Six decades ago, Shepard became the third woman to become a member of the Grand Ole Opry. The country music pioneer died Sunday outside Nashville.

Wells Fargo says John Stumpf and the former retail-banking head will forfeit stock awards worth about $60 million combined, after employees opened unauthorized customer accounts to meet company goals.

Viewed for decades as capitalist exploitation, tipping is now encouraged at some upscale urban restaurants catering to wealthy young customers. Restaurateurs insist it's strictly voluntary.

NPR annotated the first presidential debate debate with fact check, analysis and context.

An enormous television audience was expected for the first Clinton-Trump presidential debate. Crowds of voters also gathered in homes, restaurants and bars to watch the candidates go toe to toe.

Native Americans make up less than 1 percent of students in college. Many say they feel invisible, without access to elite campuses. One program helps them leverage their heritage and identity.