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In a year of big headlines, Fresh Air dove deep on topics ranging from the magnificent to the microscopic. Listen back to our conversations with scientists, comedians, authors, journalists and more.

Democrats will hold 12 presidential primary debates. The Democratic National Committee says it will have about one a month through the process.

Homeland Security Secretary Kirstjen Nielsen said Thursday that migrants entering the U.S. from Mexico — regardless of country of origin — must wait in Mexico while their claims are heard.

The Agriculture Department wants to limit states' ability to apply for exemption waivers. It wants more able-bodied people to work in exchange for federal food benefits.

Scholars at the U.S. Holocaust Memorial Museum say that mass killings follow predictable patterns. They're using a computer model to track where the next genocide is likely to occur.

The second-busiest airport in Britain had to cancel hundreds of flights and even had to get the military involved. Authorities say the perpetrator is still on the loose.

The explosion in online holiday shopping means billions of packages need to be delivered — and companies like UPS, FedEx and Amazon are under more pressure than ever.

If the decision of a judge in Texas to invalidate the federal health law holds up, expect broad effects on your health care — from insurance coverage to Medicare payments to pre-existing conditions.

As efforts to get farmers to stop growing coca in favor of legal crops falter, some farmers feel abandoned. But one man says he'll stand by them, helping farmers shift to cacao for high-end chocolate.

New Yorker reporter Ben Taub says hundreds of thousands of Iraqi civilians, including women and children, are being detained, tortured, killed or cast out for suspected association with ISIS.