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The stakes are high as the U.S. and Iran begin negotiations Friday on Iran's nuclear program. If they can't reach a deal, President Trump could order a military strike.

NPR's Steve Inskeep talks to former National Security Adviser Jake Sullivan about the negotiations between the U.S. and Iran ahead of Friday's talks in Oman.

As the U.S. and Iran prepare to hold nuclear talks in Oman Friday, people in Iran are facing an intense crackdown as security forces track down anyone who was involved in the anti-government protests

Tens of millions of Americans are expected to tune in on Sunday to watch Super Bowl LX. NPR speaks with sports journalist Kevin Blackistone to get ready for the big game.

Don Crisman and Gregory Eaton have never missed a Super Bowl. On Sunday, they'll attend their 60th game.

Under Trump administration deals to lower drug prices, pharmaceutical companies are offering some of their drugs at discounted prices through a new website called TrumpRx.gov.

The Bureau of Ocean Energy Management is evaluating whether to hold a first-of-its-kind lease sale for seabed mineral development in federal waters off Alaska, and seeking information and input to help decide if it should move forward.

The Trump administration is reducing the number of immigration officers in Minnesota by 700, but there's still no end date for the surge despite weeks of turmoil and the deaths of two U.S. citizens.

NPR's Leila Fadel asks Minnesota Attorney General Keith Ellison what concessions leaders in his state are willing to make to secure a further withdrawal of federal immigration agents.

As Nigeria battles multiple security crises, a single attack in the west left more than 160 people dead and raises new questions about who's really in control.